Index Entries

Xue Li, Jos van Geffen, Michiel van Weele, Xiaomeng Zhang, Yazhou He, Xiangrui Meng, Maria Timofeeva, Harry Campbell, Malcolm Dunlop, Lina Zgaga, and Evropi Theodoratou
September 14, 2021
Scientific Reports

Abstract: A growing body of evidence suggests that vitamin D deficiency has been associated with an increased susceptibility to viral and bacterial respiratory infections. In this study, we aimed to examine the association between vitamin D and COVID-19 risk and outcomes. We used logistic regression to identify associations between vitamin D variables and COVID-19 (risk of infection, hospitalisation and death) in 417,342 participants from UK Biobank… Ambient UVB was strongly and inversely associated with COVID-19 hospitalization and death overall and consistently after stratification by BMI and ethnicity. We also observed an interaction that suggested greater protective effect of genetically-predicted vitamin D levels when ambient UVB radiation is stronger.

Introduction: [E]vidence suggests that COVID-19 disproportionately affects black and minority ethnic individuals, with one potential explanation being the higher prevalence of vitamin D deficiency, in addition to other risk factors. It is thus hypothesised that having adequate vitamin D levels may help reduce the risk of contracting the SARS-CoV-2 virus or reduce the risk of severe or lethal COVID-19 disease."

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COVID-19,medical treatments,nutraceuticals,vitamin D