Case Report
"In February 2021, the patient, a 20-year-old female, presented to an emergency room...due to anaphylaxis following administration of the Pfizer/BioNTech COVID-19 vaccine. Approximately 10 min after vaccination, she developed headache and elevated heart rate, which she attributed to feelings of anxiety regarding vaccination. However, 5 min later, the patient noted having angioedema and cramping abdominal pain. She self-administered intramuscular epinephrine and oral diphenhydramine...
Emergency Department and Hospital Course and Follow-Up
In the emergency department, patient had worsening gastrointestinal symptoms, including emesis. An additional dose of epinephrine was administered...the patient was admitted...On the day of discharge, the patient's gastrointestinal symptoms had resolved although she continued to experience headache, dizziness, and generalized weakness...
Discussion
This report describes anaphylaxis to the Pfizer/BioNTech COVID-19 vaccine in a patient who was later confirmed to be allergic to polyethylene glycol. This report... support[s] the need for individuals with suspected allergy to PEG to consult an allergist prior to vaccination..."
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