"Letter to the Editor
... Neurological adverse reactions to SARS-CoV-2 vaccinations include exacerbation or new onset neuro-immunologic disease, such as myasthenia, Guillain-Barre syndrome, immune encephalitis, or multiple sclerosis but also ischemic stroke or intra-cerebral bleeding (ICB). ICB may be due to hypocoagulability, or immune-mediated thrombotic thrombocytopenia. Even if patients do not experience side effects after the first dosage, they may develop severe neurological complications after the second dose, as in the following case.
The patient is a 52yo non-smoking, HIV-negative male, who experienced sudden-onset difficulties with reading and speaking seven days after the second dose of an mRNA-based SARS-CoV-2 vaccine. He did not experience any side effects immediately after the first or second vaccination...
The presented patient is interesting for ICB shortly after the second dose of an mRNA-based SARS-CoV-2 vaccine. Whether there was a causal relation between vaccination and the ICB remains speculative. Arguments for a causal relation are that ICB has been reported as a complication of a SARS-CoV-2 vaccination, that ICB occurred time-linked to the vaccination, and that arterial hypertension can be a complication of a SARS-CoV-2 vaccination. A further argument in favour of a causal relation is that ICB has been repeatedly reported as a complication of infections with SARS-CoV-2."
© 2021 International Hemorrhagic Stroke Association. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).