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Eran Bendavid, Christopher Oh, Jay Bhattacharya, and John P. A. Ioannidis
January 5, 2021
European Journal of Clinical Investigation

Results: … In none of the 8 countries and in none out of the 16 comparisons (against Sweden or South Korea) were the effects of mrNPIs [more restrictive nonpharmaceutical interventions] significantly negative (beneficial).”

Discussion: In the framework of this analysis, there is no evidence that more restrictive non-pharmaceutical interventions (‘lockdowns’) contributed substantially to bending the curve of new cases in England, France, Germany, Iran, Italy, the Netherlands, Spain, or the United States in early 2020. By comparing the effectiveness of NPIs on case growth rates in countries that implemented more restrictive measures with those that implemented less restrictive measures, the evidence points away from indicating that mrNPIs (major interventions) provided additional meaningful benefit above and beyond lrNPIs (light interventions) …

In summary, we fail to find strong evidence supporting a role for more restrictive NPIs in the control of COVID in early 2020. We do not question the role of all public health interventions, or of coordinated communications about the epidemic, but we fail to find an additional benefit of stay-at-home orders and business closures. The data cannot fully exclude the possibility of some benefits. However, even if they exist, these benefits may not match the numerous harms of these aggressive measures. More targeted public health interventions that more effectively reduce transmissions may be important for future epidemic control without the harms of highly restrictive measures.”

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lockdowns