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Norain Talib, Matteo Fronza, Constantin Arndt Marschner, Paaladinesh Thavendiranathan, Gauri Rani Karur, and Kate Hanneman
March 11, 2024
Journal of Cardiovascular Magnetic Resonance
University of Toronto

"Background: The purpose of this study was to evaluate cardiovascular magnetic resonance (CMR) findings and their relationship to longer-term clinical outcomes in patients with suspected myocarditis following coronavirus disease 2019 (COVID-19) vaccination.

Methods: Consecutive adult patients who underwent clinically indicated CMR for evaluation of suspected myocarditis following messenger ribonucleic acid (mRNA)-based COVID-19 vaccination at a single center between 2021 and 2022 were retrospectively evaluated. Patients were classified based on the revised Lake Louise criteria for T1-based abnormalities (late gadolinium enhancement [LGE] or high T1 values) and T2-based abnormalities (regional T2-hyperintensity or high T2 values).

Results: Eighty-nine patients were included... In the subset of 21 patients who met both T1- and T2-criteria at baseline and had follow-up CMR, myocardial edema had resolved and left ventricular ejection fraction had normalized in all at median imaging follow-up of 214 days (IQR 132–304). However, minimal LGE persisted in 10 (48%)."

 

 

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COVID-19,heart disorders,vaccines