“Methods: We conducted an uncontrolled non-comparative observational study in a cohort of 80 relatively mildly infected inpatients treated with a combination of hydroxychloroquine and azithromycin over a period of at least three days, with three main measurements: clinical outcome, contagiousness as assessed by PCR and culture, and length of stay in infectious disease unit (IDU).
Results: All patients improved clinically except one 86 year-old patient who died, and one 74 year-old patient still in intensive care. A rapid fall of nasopharyngeal viral load was noted, with 83% negative at Day7, and 93% at Day8. Virus cultures from patient respiratory samples were negative in 97.5% of patients at Day5. Consequently patients were able to be rapidly discharged from IDU with a mean length of stay of five days…
Introduction: … According to an online survey conducted at the end of March, 33% of an international panel of physicians reported personally prescribing (or seeing colleagues prescribe) hydroxychloroquine (or chloroquine), and 41% reported the same for azithromycin (or similar antibiotics) to fight COVID-19. In addition, of those who have treated COVID-19 patients, 37% believe that hydroxychloroquine (or chloroquine) is the most effective therapy against the disease, and 32% believe the same for azithromycin (or similar antibiotics).”
© 2020 Elsevier Ltd. All rights reserved. Elsevier user license Articles published under an Elsevier user license are protected by copyright. Users may access, download, copy, translate, text and data mine (but may not redistribute, display or adapt) the articles for non-commercial purposes provided that users: Cite the article using an appropriate bibliographic citation (i.e. author(s), journal, article title, volume, issue, page numbers, DOI and the link to the definitive published version on ScienceDirect) Maintain the integrity of the article Retain copyright notices and links to these terms and conditions so it is clear to other users what can and cannot be done with the article Ensure that, for any content in the article that is identified as belonging to a third party, any re-use complies with the copyright policies of that third party Any translations, for which a prior translation agreement with Elsevier has not been established, must prominently display the statement: "This is an unofficial translation of an article that appeared in an Elsevier publication. Elsevier has not endorsed this translation." Source: https://www.elsevier.com/about/policies/open-access-licenses/elsevier-user-license