Continued mass vaccination will only push the evolutionary capacity of SARS-CoV-2 Spike protein beyond the Omicron version

“Scientific naivete combined with arrogant megalomania has led the mighty alliance of PHKOL and Industry to dramatically underestimate the evolutionary capacity of SARS-CoV-2 when it is put under widespread immune pressure. There can be no doubt that Omicron is only one such example of this and that other variants harboring a similar panoply of S-directed mutations will soon emerge in other countries. There is, indeed, no reason to believe that identical conditions of suboptimal population-level immune pressure on SARS-CoV-2 infectiousness combined with widespread infectious pressure would lead to different results. Alternatively, countries which – thanks to mass vaccination – have prepared their populations to serve as an excellent breeding ground for more infectious variants will exhibit a high level of hospitality to Omicron and its peers…

Mass vaccination promotes viral resistance to C-19 vaccines. Viral resistance drives enhanced infectiousness of SARS-CoV-2 (e.g., Omicron) and may ultimately enable SARSCoV-2 to utilize alternative cell surface determinants to enter permissive cells…

It is undeniable that mass vaccination will only drive the virus to fully exploit its evolutionary capacity, including – if needed – its ability to use alternate receptor domains on permissive cells. The fitness cost that may come with such a dramatic mutation is likely to be rewarded with enhanced pathogenicity. I am truly afraid that these dynamics will eventually allow for the natural selection of individuals with uncompromised innate immunity while eliminating those without it. While such natural selection would lead to an eradication of SARS-CoV-2 as innate immunity sterilizes the virus and blocks transmission, the consequences would be unimaginable – the price paid for ending the pandemic by virus eradication is not comparable to the one paid for by generating herd immunity and allowing the virus to enter an endemic state. Those who are enforcing mass vaccination are opting for the former instead of the latter, an act that will be remembered as the deadliest sin ever.”