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Barak Mizrahi, Roni Lotan, Nir Kalkstein, Asaf Peretz, Galit Perez, Amir Ben-Tov, Gabriel Chodick, Sivan Gazit, and Tal Patalon
July 31, 2021
Maccabi Healthcare Services (Israel)

This is a preprint paper.

Abstract: … Leveraging the centralized computerized database of Maccabi Healthcare Services (MHS), we assessed the correlation between time-from-vaccine and incidence of breakthrough infection. We found that the risk for infection was significantly higher for early vaccinees compared to those vaccinated later…

Main: Individuals who were vaccinated in January 2021 had a 2.26-fold increased risk (CI 1.80-3.01) for breakthrough infection compared to individuals who were vaccinated in April 2021 (Figure 1).

In this cohort of MHS members, all of whom are vaccinated with the BioNTech/Pfizer mRNA BNT162b2 vaccine in a two-dose regimen, we identified a significant correlation between time-from-vaccine and afforded protection against SARS-CoV-2 infection. The risk for breakthrough infection was significantly higher for early vaccinees compared to those vaccinated later.”

document
breakthrough cases,COVID-19,vaccines,clinical cases