"Introduction
... In this case study, we report a patient that presented with AHEM [acute hemorrhagic encephalomyelitis], systemic venous thromboembolism, and subsequent presence of moderate/high levels of aPL [antiphospholipid] antibodies, indicating a possible APS [antiphospholipid syndrome], following the second Pfizer-BioNTech COVID-19 vaccination. The case illustrates the diagnostic and therapeutic challenges in a patient with fulminant progression of CNS [central nervous system] inflammation and thromboembolism and complicating preceding autoimmune disease, immunosuppressive treatment and vaccination.
Case Description
A 53-year-old man developed confusion and unconsciousness over a few hours and presented at the emergency room with a Glascow Coma Scale of 7, agitation, and snoring... Neurological examination revealed anisocoria, right side miosis, bilateral absence of pupillary light reflex, and reduced voluntary movements in the left arm and leg. The patient was afebrile without clinical or laboratory signs of infection. He was intubated and admitted to the intensive care unit...
Conclusions
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