"Introduction
... Here, we present the first published case report of post-vaccination acute diverticulitis and colon micro-perforation following a Moderna booster dose in a young adult.
Case presentation
Our patient was a 41-year-old Caucasian male with a past medical history of bipolar depression, asthma, and obesity... who presented to the emergency room (ER) with the chief complaint of abdominal pain. The patient had received a Moderna COVID-19 vaccine booster dose the day prior to presentation to the ER. On the morning of the day of presentation to the ER, the patient started experiencing diarrhea and progressively worsening sharp, intermittent, generalized abdominal pain associated with sweating and loss of appetite... The patient had tolerated the first two doses of the vaccine without any adverse events...
Conclusions
... COVID-19 vaccine recipients should be properly educated on the complete adverse event profile of the vaccines. We also recommend vaccine recipients with pre-existing GI tract diseases, including those with a history of GI bleeding, inflammatory bowel disease (IBD), or peptic ulcer disease should be warned of the potential GI tract-related adverse events and closely monitored. Appropriate hydration should be promoted post-vaccination in addition to replacing electrolytes (with oral rehydration solution) in cases of intractable diarrhea, or when vaccine recipients experience GI bleeding, prompt medical attention should be sought to prevent hemorrhagic shock and reduce mortality/morbidity."
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Ajmera et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.