Index Entries

Christopher Martin Allen iBSc, MBBS, MRCP; Shelby Ramsamy MBChB, MRCP; Alexander William Tarr BSc, PhD; Patrick Jason Tighe BSc, PhD; William Lucien Irving MB BChir, MA, PhD, MRCP, FRCPath; Radu Tanasescu MD, PhD; and Jonathan Rhys Evans MB BChir, MA, PhD, MRCP
June 10, 2021
Annals of Neurology

Abstract: Although SARS-CoV-2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain–Barré syndrome (GBS) occurring within 3 weeks of vaccination with the Oxford–AstraZeneca SARS-CoV-2 vaccine. This rare neurological syndrome has previously been reported in association with SARS-CoV-2 infection itself. Our cases were given either intravenous immunoglobulin, oral steroids, or no treatment. We suggest vigilance for cases of bifacial weakness with paresthesias variant GBS following vaccination for SARS-CoV-2 and that postvaccination surveillance programs ensure robust data capture of this outcome, to assess for causality.”

             

document
adverse events,COVID-19,neurological disorders,vaccines