"Early treatment shows 65% [54‑74%] lower risk with pooled effects in 38 studies. Results are similar for higher quality studies and for peer-reviewed studies. The 16 mortality and 16 hospitalization results show 76% [60‑86%] lower mortality and 41% [28‑51%] lower hospitalization.
HCQ reduces risk for COVID-19 with very high confidence for mortality, hospitalization, cases, viral clearance, and in pooled analysis, however increased risk is seen with very low confidence for ventilation.
We show traditional outcome specific analyses and combined evidence from all studies, incorporating treatment delay, a primary confounding factor in COVID-19 studies.
Real-time updates and corrections, transparent analysis with all results in the same format, consistent protocol for 57 treatments."
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