Letter to the Editor: Previous COVID-19 infection, but not Long-COVID, is associated with increased adverse events following BNT162b2/Pfizer vaccination

“This study of healthcare workers demonstrated that prior COVID-19, but not Long-COVID, was associated with increased risk of AEs [adverse events] following BNT162b2/Pfizer vaccination, although there was no relationship with duration since COVID-19 illness. Women and younger individuals were also more likely to report AEs. Our study adds to other reports supporting the wider understanding of AEs following COVID-19 vaccination. Importantly, given hesitancy surrounding recently developed COVID-19 vaccines, our findings may help inform those with previous COVID-19 of increased susceptibility to certain AEs. Our study also adds weight to the question of whether a second dose of mRNA vaccine is necessary in those with previous COVID-19, assuming effective immunity is established after the first dose. This is relevant, given that Tre-Hardy's and other studies have reported worse AEs following second doses of vaccine.”