"Discussion: TM [transverse myelitis] is a neurological disorder characterized by inflammation of the spinal cord without a compressive lesion. Most commonly it is associated with multiple sclerosis, neuromyelitis optica and infections. TM manifests as an acute or sub-acute sensorimotor and autonomic dysfunction and sphincter disturbance ...
Given .5 per million incidences of Covid-19-associated TM, the incidence of TM associated with Covid-19 vaccine appears to be considerable. With widespread vaccination, increasing number of cases with post-vaccine TM have been reported. The underlying mechanisms of AstraZeneca vaccine-induced TM are not yet known, it has been proposed that either the virus structural surface vector glycoprotein antigen or its chimpanzee adenovirus adjuvant could be the trigger for the autoimmunity process.
In our case, after extensive workup, patientʻs symptoms could not be better explained by any alternative etiology other than post-vaccination TM. We believe her symptoms could not be associated with Covid-19 infection since she had negative PCR results both before and after vaccination and did not report any symptoms of Covid-19."
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