Index Entries

Matthew E. Oster, David K. Shay, John R. Su, Julianne Gee, C. Buddy Creech, Karen R. Broder, Kathryn Edwards, Jonathan H. Soslow, Jeffrey M. Dendy, Elizabeth Schlaudecker, Sean M. Lang, Elizabeth D. Barnett, Frederick L. Ruberg, Michael J. Smith, M. Jay Campbell, Renato D. Lopes, Laurence S. Sperling, Jane A. Baumblatt, Deborah L. Thompson, Paige L. Marquez, Penelope Strid, Jared Woo, River Pugsley, Sarah Reagan-Steiner, Frank DeStefano, and Tom T. Shimabukuro
January 25, 2022
JAMA (Journal of the American Medical Association)
CDC (Centers for Disease Control & Prevention)

Findings: In this descriptive study of 1626 cases of myocarditis in a national passive reporting system, the crude reporting rates within 7 days after vaccination exceeded the expected rates across multiple age and sex strata. The rates of myocarditis cases were highest after the second vaccination dose in adolescent males aged 12 to 15 years (70.7 per million doses of the BNT162b2 vaccine), in adolescent males aged 16 to 17 years (105.9 per million doses of the BNT162b2 vaccine), and in young men aged 18 to 24 years (52.4 and 56.3 per million doses of the BNT162b2 vaccine and the mRNA-1273 vaccine, respectively).

Meaning: Based on passive surveillance reporting in the US, the risk of myocarditis after receiving mRNA-based COVID-19 vaccines was increased across multiple age and sex strata and was highest after the second vaccination dose in adolescent males and young men.”

document
adverse events,COVID-19,heart disorders,mRNA,vaccines