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Mayuko Yamamoto, Misaki Kase, Hozumi Sano, Reiko Kamijima, and Shigetoshi Sano
August 25, 2022
Journal of Cutaneous Immunology and Allergy
Kochi University (Japan)

Introduction: Global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19), which was spread from China in 2019, urged development of COVID-19 vaccines. Until now, a number of cutaneous reactions after COVID-19 vaccination has been reported worldwide, including injection site reaction or so called COVID arm, urticarial reaction, morbilliform rash, vesicopapular lesions, pityriasis rosea-like lesion, purpura, vasculitis, thrombus, ulcer, and reactivation of herpesviruses.

Previous study revealed that the most frequent skin reactions were COVID arm in women (38.1%) and varicella zoster virus (VZV) reactivation in men (20%). The underlying pathomechanism for the mRNA COVID-19 vaccination-associated skin reactions (hereafter referred to as CVSRs) largely remains unknown… Here, we present a case of persistent VZV infection after COVID-19 vaccination.”

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adverse events,COVID-19,mRNA,shingles (herpes zoster) and chickenpox (herpes varicella),vaccines