“Abstract
Methodology/Principal Findings: We conducted a cluster randomized controlled trial of households (composed of at least 3 members) where an index subject presented with influenza-like-illness of <48 hours duration. After influenza was confirmed in an index case… the household of the index subject was randomized to 1) control or 2) surgical facemasks or 3) hand hygiene...
Methods
Objectives: The overall objective of the study was to quantify the efficacy of face masks and/or hand hygiene in reducing transmission of influenza to household contacts at the individual level…
Results
... Of the 944 recruited subjects, 198 met the criteria for randomization and further follow-up.
Discussion
…[W]e found little effect of the interventions in preventing household transmission."
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