Index Entries

Kristin Goddard, Ned Lewis, Bruce Fireman, Eric Weintraub, Tom Shimabukuro, Ousseny Zerbo, Thomas G. Boyce, Matthew E. Oster, Kayla E. Hanson, James G. Donahue, Pat Ross, Allison Naleway, Jennifer C. Nelson, Bruno Lewin, Jason M. Glanz, Joshua T.B. Williams, Elyse O. Kharbanda, W. Katherine Yih, and Nicola P. Klein
August 19, 2022
Vaccine
Kaiser Permanente Northern California

"Background: Evidence indicates that mRNA COVID-19 vaccination is associated with risk of myocarditis and possibly pericarditis, especially in young males. It is not clear if risk differs between mRNA-1273 versus BNT162b2. We assessed if risk differs using comprehensive health records on a diverse population...

Results: From December 14, 2020 – January 15, 2022 there were 41 cases after 2,891,498 doses of BNT162b2 and 38 cases after 1,803,267 doses of mRNA-1273. Cases had similar demographic and clinical characteristics. Most were hospitalized for ≤1 day; none required intensive care. During days 0–7 after dose 2 of BNT162b2, the incidence was 14.3 (CI: 6.5–34.9) times higher than the comparison interval, amounting to 22.4 excess cases per million doses; after mRNA-1273 the incidence was 18.8 (CI: 6.7–64.9) times higher than the comparison interval, amounting to 31.2 excess cases per million doses."

Myocarditis and pericarditis during the 0–7-day risk interval post-vaccination versus the comparison interval 22–42 days post-vaccination, in 18–39-year-olds, by product and dose, December 14, 2020–January 15, 2022

document
COVID-19,heart disorders,vaccines