“Abstract: Memory T cells contribute to rapid viral clearance during re-infection, but the longevity and differentiation of SARS-CoV-2-specific memory T cells remain unclear. Here we conduct ex vivo assays to evaluate SARS-CoV-2-specific CD4+ and CD8+ T cell responses in COVID-19 convalescent patients up to 317 days post-symptom onset (DPSO), and find that memory T cell responses are maintained during the study period regardless of the severity of COVID-19. In particular, we observe sustained polyfunctionality and proliferation capacity of SARS-CoV-2-specific T cells.”
Springer Nature © 2023 Springer Nature Limited
This paper was published under Open Access.
What is open access (OA)?
Articles that are published OA are freely available online, and are published under a Creative Commons CC-BY license, which allows for reuse and sharing. The publishing costs are covered by the author’s institution or funding body paying an Article Processing Charge (APC).