Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on reports of Guillain-Barré Syndrome (GBS) following adenovirus vector COVID-19 vaccines

"Guillain-Barré Syndrome (GBS)... is a rare immune system disorder that results in muscle weakness, pain or numbness, and, in more severe cases, paralysis...

Based on a careful scientific review of the available information, the GACVS [WHO Global Advisory Committee on Vaccine Safety] subcommittee came to the following conclusions and recommendations:

• Rare cases of GBS have been reported following vaccinations with adenovirus vector COVID-19 vaccines...
• More rigorous studies using alternative data sources and robust study designs, and comparison of vaccinated and unvaccinated populations would be needed, to fully assess the significance of these events."