Index Entries

Muhammad Bilal Khalid and Pamela A. Frischmeyer-Guerrerio
February 2023
JACI Global: The Journal of Allergy and Clinical Immunology
National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH)

"Abstract

... These reactions [anaphylaxis to the mRNA vaccines] occurred predominantly in young to middle-aged females, and many had a history of allergies...

Anaphylaxis is a potentially life-threatening allergic reaction requiring immediate medical intervention... In this review, we discuss the evolution of current management strategies and highlight the gaps in our understanding to emphasize areas warranting additional research...

Conclusions

... Anaphylaxis to... [Covid mRNA] vaccines has been reported at least 3 times more commonly compared with the cumulative risk of vaccine anaphylaxis or other commonly administered vaccines, such as the influenza vaccine... Currently, the mechanism of these anaphylactic reactions is unclear, although PEG [polyethylene glycol] appears to have much less of a role than previously thought..."

document
adverse events,COVID-19,lipid nanoparticles,vaccine ingredients,vaccines