Index Entries

Tawanda Chivese, Joshua T. Matizanadzo, Omran A. H. Musa, George Hindy, Luis Furuya-Kanamori, Nazmul Islam, Rafal Al-Shebly, Rana Shalaby, Mohammad Habibullah, Talal Al-Marwani, Rizeq F Hourani, Ahmed D Nawaz, Mohammad Z Haider, Mohamed M. Emara, Farhan Cyprian, and Suhail A. R. Doi
January 31, 2022
Qatar University

Methods and analyses: A synthesis of existing research was conducted. The Cochrane Library for COVID-19 resources, the China Academic Journals Full Text Database, PubMed, and Scopus as well as preprint servers were searched for studies conducted between 1 January 2020 to 1 April 2021. We included studies with the relevant outcomes of interest. All included studies were assessed for methodological quality and pooled estimates of relevantoutcomes were obtained in a meta-analysis using a bias adjusted synthesis method…

Results: Fifty-four studies, from 18 countries, with a total of 12 011 447 individuals, followed up to 8 months after recovery, were included. At 6-8 months after recovery, the prevalence of detectable SARS-CoV-2 specific immunological memory remained high; IgG – 90.4% …, CD4+ - 91.7%..., and memory B cells 80.6%... and the pooled prevalence of reinfection was 0.2%. Individuals who recovered from COVID-19 had an 81% reduction in odds of a reinfection.

Conclusion: Around 90% of people previously infected with SARS-CoV-2 had evidence of immunological memory to SARS-CoV-2, which was sustained for at least 6-8 months after recovery, and had a low risk of reinfection.”

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COVID-19,health statistics,natural immunity