“Discussion: Recent observations by Ramakrishnan et al. suggest that the inhaled corticosteroid budesonide reduces clinical recovery times and prevents progression and clinical deterioration during mild COVID-19 infection… [W]e observed significant reduction of viral titers for all viral variants in vitro when cells were treated with 25 µM budesonide. These results are in accordance with previous studies that demonstrated the suppression of SARS-CoV-2 and MERS-CoV RNA copy number by targeting the viral replication–transcription complex.”
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