Cardiac Multiple Micro-Scars: An Autopsy Study

Case Summary: Multiple micro-scars (MMS) found in the myocardium of 3 patients who died of unexplained cardiac arrest were presented at our clinicopathology conference. Upon review of the clinical record, patients with MMS before death had arrhythmia (ie, atrial fibrillation and nonsustained ventricular tachycardia, including new onset). Interestingly, MMS were found in the left ventricle, the junction of the pulmonary vein and left atrium, and the right ventricle and right atrium. All 3 patients had histories of COVID-19 booster vaccination, and 1 of the 3 patients had a history of COVID-19.

 

 

... A global survey showed that any type of COVID-19 vaccine appears to instigate cardiac arrhythmias, and COVID-19 vaccines may lead to cardiac conduction abnormalities. These mechanisms are speculated to arise from molecular mimicry or spike protein production, an escalated inflammatory response, and the eventual scar and fibrosis. "