Clinical and Molecular Characterization of a Rare Case of BNT162b2 mRNA COVID-19 Vaccine-Associated Myositis

URL

https://www.mdpi.com/2076-393X/10/7/1135

Authors

Eli Magen, Sumit Mukherjee, Mahua Bhattacharya, Rajesh Detroja, Eugene Merzon, Idan Blum, Alejandro Livoff, Mark Shlapobersky, Gideon Baum, Ran Talisman, Evgenia Cherniavsky, Amir Dori, and Milana Frenkel-Morgenstern

Published Date

July 16, 2022

Publication

Vaccines

Organization

Barzilai University Medical Center (Israel)

Key Excerpts

"Abstract: Here, we report a rare case of myositis after injection of the first dose of BNT162b2 COVID-19 mRNA vaccine into the left deltoid muscle of a 34-year-old, previously healthy woman who presented progressive proximal muscle weakness, progressive dysphagia, and dyspnea with respiratory failure. One month after vaccination, BNT162b2 vaccine mRNA expression was detected in a tissue biopsy of the right deltoid and quadriceps muscles."

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Medium

document

Topics

COVID-19,gene therapy,mRNA,SARS-CoV-2 spike protein,vaccine systemic and virological concerns,vaccines