Female reproduction and abnormal uterine bleeding after COVID-19 vaccination

"Introduction

... The Korean Specialized Committee for the compensation of loss after COVID-19 vaccination has decided to include abnormal uterine bleeding (AUB) as a 'suspected related symptom' after COVID-19 vaccination on August 16, 2021, for all vaccine types, including those manufactured by Oxford-AstraZeneca, Moderna, Pfizer-BioNTech, and J&J. This decision has enabled those who developed AUB after vaccination for COVID-19 to claim compensation from the committee and receive support. The scientific basis for this decision was the analysis by the COVID-19 Vaccine Safety Committee of the National Academy of Medicine of Korea. After a comprehensive analysis of domestic and international data on adverse reactions reported after COVID-19 vaccination, the committee has announced the discovery of a statistically significant association between AUB and COVID-19 vaccination, which is sufficient evidence to establish a causal relationship.

This article specifically focuses on the effect of COVID-19 vaccines on female reproductive health, including thrombosis, ovarian function, in vitro fertilization (IVF) outcomes, and the menstrual cycle...

COVID-19 vaccination and the menstrual cycle

... 4. Menstrual severity: Menorrhagia has also been commonly reported after COVID-19 vaccination. An Israeli survey of 7,904 pre-menopausal non-pregnant women by Issakov et al. reported that 80.6% of those who reported menstrual alterations had menorrhagia, the most common menstrual problem encountered by the COVID-19 vaccinated population. In a study by Wong et al., menstrual severity, or heavy bleeding, was the second most commonly reported event (67.0%). Another retrospective study reported heavy menstrual bleeding among 41.8% of 184 patients with menstrual alterations."