Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals

URL

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00204-4?

Authors

Alison Tarke, John Sidney, Nils Methot, Esther Dawen Yu, Yun Zhang, Jennifer M. Dan, Benjamin Goodwin, Paul Rubiro, Aaron Sutherland, Eric Wang, April Frazier, Sydney I. Ramirez, Stephen A. Rawlings, Davey M. Smith, Ricardo da Silva Antunes, Bjoern Peters, Richard H. Scheuermann, Daniela Weiskopf, Shane Crotty, Alba Grifoni, and Alessandro Sette

Published Date

July 1, 2021

Publication

Cell Reports Medicine

Organization

La Jolla Institute for Immunology (California)

Key Excerpts

“Highlights: T cells of exposed donors or vaccinees effectively recognize SARS-CoV-2 variants

Summary: … [T]he SARS-CoV-2 variants analyzed here do not significantly disrupt the total SARS-CoV-2 T cell reactivity”

User License: Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0) | Elsevier's open access license policy

Medium

document

Topics

COVID-19,natural immunity