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Josè Vitale, Nicola Mumoli, Pierangelo Clerici, Massimo De Paschale, Isabella Evangelista, Marco Cei, and Antonino Mazzone
May 28, 2021
JAMA Internal Medicine
Magenta Hospital and Legnano Hospital (Italy)

Methods: We investigated the incidence of SARS-CoV-2 primary infection and reinfection among individuals who, during the first wave of the pandemic in Italy (February to July 2020), underwent diagnostic reverse-transcriptase–polymerase chain reaction (PCR)…

Results: … During the follow-up (mean [SD], 280 days) 5 reinfections … were confirmed in the cohort of 1579 positive patients…

Discussion: The study results suggest that reinfections are rare events and patients who have recovered from COVID-19 have a lower risk of reinfection. Natural immunity to SARS-CoV-2 appears to confer a protective effect for at least a year.”

document
breakthrough cases,COVID-19,natural immunity,polymerase chain reaction (PCR) testing issues,reverse transcription