"Abstract
Here we performed bioinformatic analysis to investigate the interaction of S2 subunit protein of SARS-nCoV-2 of novel coronavirus with tumor suppressor proteins p53 and BRCA-1/2.
... p53 and BRCA ... regulate downstream genes in response to numerous cellular stress and are frequently mutated in human cancer. Interestingly we found p53, BRCA-1 and BRCA-2 interact with heptic repeat-2 region of S2 subunit through C- terminal domain. This short bioinformatic analysis is a first time report and significant since COVID-19 is more fatal in people with underlying conditions specially lung diseases, diabetes and cancer."
© 2020 The Authors. Published by Elsevier Inc. on behalf of Neoplasia Press, Inc. This is an open access article under the CC BY-NC-ND license.