"Abstract
... We report a case of TCM [takotsubo cardiomyopathy] following the COVID-19 vaccine in a 59-year-old female who presented with intermittent chest pain and dyspnea following the COVID-19 vaccine booster dose.
Discussion
The symptoms of TCM often mimic those of acute myocardial infarction. Patients may experience chest pain or discomfort, dyspnea, tachycardia or irregular pulse with EKG changes, dizziness, fainting, or low blood pressure, which may indicate coronary artery disease with a raised level of myocardial enzymes in the absence of remarkable coronary artery stenosis on angiography... COVID-19 vaccine, especially the mRNA vaccine, can also potentially cause TCM...
Our patient... was diagnosed with TCM. She had no identifiable trigger for TCM, including stress, emotional and physical trauma. Her COVID-19 PCR was negative. Moreover, she had no identifiable risk factor for cardiovascular disease, normal creatine kinase level, and absence of obstructive or thrombotic lesion or coronary angiography in the presence of EKG, and echocardiography findings justify that ischemic heart disease was unlikely. Massive immune response after the COVID-19 vaccine may have contributed to the development of TCM."
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Reza et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.