"Abstract
Background: COVID-19 vaccines have had expedited reviews without sufficient safety data. We wanted to compare risks and benefits.
Methods: We calculated the Number Needed to Vaccinate (NNTV) to prevent one death from a large Israeli field study. We accessed the Adverse Drug Reactions database of the Dutch National Register
(Lareb) to extract the number of cases reporting severe side-effects and the number of cases reporting fatal side-effects.
Results: The NNTV is between 200 and 700 to prevent one case of COVID-19 for the mRNA vaccine marketed by Pfizer. NNTV to prevent one death is between 9,000 and 100,000 (95% confidence interval), with 16,000 as a point estimate. "
Copyright © The Authors — Published Under the Creative Commons License Share/Alike (see https://creative commons.org/licenses/)